This endogenous tripeptide (glycin, cysteine & glutamic acid) is present in almost all cells of the body playing a role in the detoxification and excretion of drugs and xenobiotics. Glutathione is primarily produced in the liver (about 8-10 grams daily in adults) and distributed to other body tissue through the bloodstream.

Optimal amounts of glutathione are necessary for supporting the immune system, and, in particular, Glutathione is required for replication of the lymphocyte immune cells. Glutathione also helps the liver to detoxify chemicals.

As pharmaceutical drug, GSH has been used as injectable form, for therapies related to ethyl alcohol or some drug intoxication (anti-neoplastic chemotherapy, anti-tubercolosis, neuroleptics, anti-depression and paracetamole, acting as antidote for poison). It also may assist in prophylaxis and treatment of the damages from ionizing radiation.

The Anatomic Therapeutic Chemical Classification defines glutathione into the category of “Antidotes” in "All other therapeutic products" (ATC code: V03AB32).

> Technical Information

CAS Number: 70-18-8
Grade: Oral and Parenteral
Appearance: White or almost white crystalline powder
Chemical name: L-γ-Glutamyl-L-cysteinylglycine
Regulatory status: DMF in CTD format
Compliance: EP
Packing size: 1 Kg, 5 Kg, 25 Kg, Double LDPE bags

As dietary supplement Glutathione provides health benefits supporting the immune system, protecting and detoxifying the liver, minimizing the risk of chronic disease, and promoting longevity.
Furthermore, especially in Asia, Glutathione has been reported to be used for its whitening effect on the skin (dark acne scars, freckles, dark underarms, age spots, etc), reversing the melanin's metabolism turning dark pigmentations (eumelanin) into light pigmentations (phaeomelanin).

Glutathione is available in chewing gum form with different dosages suitable for nutritional application. Easy to take chewing gum is a convenient way to get a daily dose of Glutathione.

 

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