The 4th Truth Pill about Vitamin K2 as MK7: ITS STABILITY IN FORMULATION
July 9th, 2019
THE STABILITY IN FORMULATION:
Is vitamin K2 suitable for formulation with calcium salt ingredients?
A very recent publication in the "Molecules" Journal has shown that purity profile of vitamin K2 as MK7 correlates with enhanced stability in formulations. MK7 raw materials, which equally comply to minimal assay and composition characteristics, may be different in terms of their purity profiles due to the presence of cis isomers and other impurities.
VitaMK7® is one of the naturally fermented MK7 ingredient tested in the study, with positive results about quality and stability. The data were obtained at 12 months, with vitaMK7® formulated with Calcium Citrate, Calcium Carbonate and Arginine. Stability data supports the formulation of vitaMK7® with the different calcium salts without the need of any coating, which would otherwise increase the number of non-natural substances.
The pure and stable MK7 ingredient like vitaMK7® minimizes the cross-reactions with other ingredients/excipients included in the formulation for the entirety of the products' shelf-life and offers an extended warranty of stability.
(Gnosis by Lesaffre)